Expert Insight View All

Foresight: The future directions of COVID-19 vaccination with bivalent BNT162b2 vaccine

From March 1, 2023, all the Coronavirus disease 2019 (COVID-19) restriction measures have been lifted in Hong Kong including the mask mandate, getting the society back to normal.1 However, there is a rebound of local COVID-19 cases caused by predominantly XBB, an Omicron sub-variant, and its descend


Professor Stephen J. Thomas, MD

Professor of Medicine, Microbiology & Immunology
Frank E. Young, MD '56 and Leanne Young Endowed Chair of Microbiology and Immunology,
Institute for Global Health and Translational Science,

SUNY Upstate Medical University

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Research Spotlight View All

Exploring the association of systemic glucocorticoids and incident major adverse cardiovascular events in patients with rheumatoid arthritis based on real-world data

Despite their exceptional anti-inflammatory properties, the use of systemic glucocorticoids (GCs) for the treatment of rheumatoid arthritis (RA) remains controversial due to the potential side effects, particularly their role in elevating patients’ risk of cardiovascular (CV) events. A po

03 Jan 2024

Dr. So, Ho

Assistant Professor,
Division of Rheumatology,
Department of Medicine and Therapeutics,
Faculty of Medicine,
The Chinese University of Hong Kong

Ann Rheum Dis. 2023.

So H, Lam TO (co-first author), Meng H, Lam SHM, Tam LS. Time and dose-dependent effect of systemic glucocorticoids on major adverse cardiovascular event in patients with rheumatoid arthritis: a population-based study. Ann Rheum Dis. 2023;82(11):1387-1393.

Navigating anticoagulation strategies for preventing recurrent events in NVAF patients with ischemic stroke despite DOAC

The increasing incidence of ischemic stroke in patients receiving direct oral anticoagulants (DOACs) highlights the heightened risk of subsequent ischemic events.1 Yet, the effectiveness and safety of antithrombotic regimens following this condition remain uncertain.1 In this investigation, patient outcomes were compared between those receiving DOACs with or without an alternative antithrombotic regimen, and the risk factors for recurrent ischemic stroke while on anticoagulation were identified.1 The 6-year study period, spanning January 1, 2015 to December 31, 2020, included 45,946 non-valvular atrial fibrillation (NVAF) patients administered DOACs for stroke prevention.1 Among them, 2,908 patients experienced an ischemic stroke despite the DOAC treatment, and 2,337 NVAF patients were included in the final analysis.1 The findings demonstrated that switching to warfarin (aHR=1.96; 95% CI: 1.27-3.02; p=0.002) or another DOAC(aHR=1.62; 95% CI: 1.25-2.11; p<0.001) was associated with an elevated risk of recurrent ischemic stroke compared with maintaining the sameDOAC therapy.1 Furthermore, the addition of an antiplatelet agent did not exhibit a reduced risk of recurrent ischemic stroke.1 The risk factors of recurrent ischemic stroke include diabetes mellitus (DM), concurrent cytochrome P450/P-glycoprotein (CYP/P-gp) modulators, and large artery atherosclerotic disease (LAD).1

30 Jun 2023

Professor Leung Wai-Hong Thomas

Head of Division of Neurology
(Academic Affairs),
Lee Quo Wei Professor of Neurology
Assistant Dean (Education),
Faculty of Medicine,
The Chinese University of Hong Kong


Dr. Ip, Yiu-Ming Bonaventure

Assistant Professor,
Department of Medicine and Therapeutics,
The Chinese University of Hong Kong

Neurology. 2023.

Ip YMB, et al. Association of Alternative Anticoagulation Strategies and Outcomes in Patients With Ischemic Stroke While Taking a Direct Oral Anticoagulant.

Meeting Highlight View All

Transforming MCL care: The potential role of BTKi-based regimens in front-line treatment

06 Sep 2023

Professor Simon Rule

Professor of Clinical Hematology,
Plymouth University Medical School,
United Kingdom
Global Clinical Head Acalabrutinib,
Haematology R&D,


Dr. Liu, Sung-Yu Herman

Specialist in Hematology and Hematological Oncology

New paradigms in hepatitis management to address treatment challenges and barriers to care


Professor Kim, Seung-Up

Department of Internal Medicine,
Yonsei University College of Medicine,
Yonsei Liver Center, Severance Hospital,
Seoul, Republic of Korea


Dr. Wong, Yu-Jun Eugene

Department of Gastroenterology & Hepatology,
Changi General Hospital
Clinical Assistant Professor,
Duke-NUS Medical School,


Decoding the spectrum of tolerance in fish allergies

04 Jan 2024

U-shaped relationship between sleep duration and T2DM regardless of traditional lifestyle risk factors

17 Nov 2023

Brain Gliosis: A Potential Origin of Persistent Post-COVID-19 Depressive and Cognitive Symptoms

17 Nov 2023

The nuanced link between prediabetes and dementia

23 Aug 2023

Connecting the dots between Parkinson’s disease and rheumatoid arthritis

12 Jul 2023

Cardio-oncology monitoring in pediatric populations - Delphi consensus recommendations from an Australian and New Zealand expert group

28 Apr 2023

Targeting TSLP for severe asthma - Tezepelumab updates from the 2023 American Academy of Allergy Asthma & Immunology Annual Meeting

06 Apr 2023

A new way out for alpha thalassemia major - Give them a chance at life with In-utero transfusions

15 Mar 2023

Beware of overlapping phenotypes in severe asthma: The eosinophilia and IgE double whammy

27 Feb 2023

Stay on the path of treatment - Take on a high-K with ease
ASN abstract highlight on sodium zirconium cyclosilicate and hyperkalemia

23 Feb 2023

Real-world effectiveness of benralizumab around the globe

06 Dec 2022

Remission is within reach - Target the underlying drivers of inflammation with benralizumab

19 Sep 2022

PACIFIC-6: Durvalumab after CRT showed similar safety profile as the PACIFIC regimen with encouraging efficacy data in frailer and older patients with stage 3, unresectable NSCLC

23 Jun 2022

Caution: The risk of severe hypoglycemia is elevated in diabetic adults with NAFLD

30 May 2022

Fiber-rich diet associated with better response to immunotherapy in patients with melanoma

25 Feb 2022

Sleep disturbance may raise the odds of certain cancers but reduce the others

10 Jan 2022

Poorer survival outcomes in breast cancer patients with chronic stress

29 Oct 2021

Infant gut microbiota is associated with an increased risk of food allergies

24 Sep 2021

Depression associated with a rapid loss in kidney function

08 Jul 2021

Potential risk factors for developing nerve damage after cancer treatment

12 May 2021

Urine test to identify and verify a patient’s type of asthma

27 Feb 2021

Potential new pinprick blood test for diagnosing HPV related-cancers

31 Dec 2020

Strategy to prevent and control NCDs in Hong Kong by 2025

30 Aug 2019

Prevalence of helicobacter pylori in symptomatic children

28 Oct 2019

Heat and gut microbiota promotes stronger bones

29 Oct 2020

A potential tumor marker for cervical cancer

31 Aug 2020

No response to exercise? The gut microbiota is to blame

29 Feb 2020

Hong Kong cancer strategy: a fight against cancer

30 Dec 2019

Clinical characteristics of the hidden carriers of COVID-19

30 Apr 2020

The use of e-cigarette or vaping products is associated with an outbreak of lung injury

29 Jun 2020