INFOGRAPGICS
Depression associated with a rapid loss in kidney function
Refining the management of hyperkalemia in the Asia-Pacific region: Consensus statements from a multidisciplinary expert panel
Hyperkalemia, defined as serum potassium >5.0mmol/L, is a potentially lethal condition as it hinders muscle function and myocardial excitability, which may contribute to arrhythmias and sudden cardiac deaths. Epidemiological data suggests the global prevalence of hyperkalemia is around 6.3%, but the
Identifying the mediators of dapagliflozin-induced renal benefits in patients with CKD with or without T2DM: Post-hoc analysis of the DAPD-CKD trial
Study Design Dapagliflozin, a sodium-glucose cotransporter 2 inhibitor (SGLT2i), has been shown to induce renal, cardiovascular (CV), and survival benefits in patients with chronic kidney disease (CKD), regardless of the presence of type 2 diabetes mellitus (T2DM) in the DAPA-CKD trial.1 Separate m
Digitized CBSM interventions demonstrate notable efficacy in reducing cancer-related anxiety and depression: The RESTORE study
Anxiety and depression are prevalent comorbidities among cancer patients, affecting an overall 33% of patients.1 About 70% of cancer patients have experienced various emotional symptoms such as fear of cancer reoccurrence, further intensifying their psychological and financial burden.1 During the AS
Sotagliflozin reduces major adverse CV events: The scored trial
Novel ASCVD risk prediction models for CKD patients: the CRIC study
Patients with chronic kidney disease (CKD) display a strong association with atherosclerotic cardiovascular disease (ASCVD) as compared with the general population.1-3 To date, there are no ASCVD risk prediction models to identify optimal treatments and prevention therapies for this high-risk population of CKD.1 A recent study published by Bundy and colleagues in the Journal of the American Society of Nephrology, developed and validated 10-year ASCVD risk prediction models among CKD patients, which included novel kidney and cardiac biomarkers to improve the prediction performance and clinical outcomes.1
Long-term evaluation of TAF vs. TDF antiviral prophylaxis in post-OLT patients with CHB
A recent randomized, phase 2 study by Gane, E.J. and colleagues presented at the American Association for the Study of Liver Diseases (AASLD): The Liver Meeting 2021 demonstrated the high long-term efficacy and safety of tenofovir alafenamide fumarate (TAF) and tenofovir disoproxil fumarate (TDF) antiviral prophylaxis in post-orthotopic liver transplant (OLT) patients with chronic hepatitis B virus (HBV) infection.1 The renal- and bone-protecting effects on patients with TAF were shown to be more profound than those with TDF.1
Management of heart failure in patients with ESKD
Heart failure (HF) is highly prevalent in patients with chronic kidney disease (CKD) and end-stage kidney disease (ESKD) and is strongly associated with mortality in these patients.1 HF in ESKD is defined based on patient-reported dyspnea assessed both pre- and post-ultrafiltration, in conjunction w
Mepolizumab provided real-world clinical benefits in patients with severe asthma stratified by common comorbidities
Asthma is a chronic inflammatory disease of the airways that affects approximately 300 million people globally with about 5-10% of asthmatics being severe asthma.1 Severe asthma typically requires treatment with high-dose inhaled corticosteroid (ICS) plus a second controller and/or systemic corticos