Professor Christoph Wanner highlights the alarming prevalence of undiagnosed CKD, especially among patients with cardiovascular conditions, where traditional screening primarily focuses on the estimated glomerular filtration rate (eGFR). He emphasizes the need to include urine albumin-creatinine ratio (uACR) testing for early diagnosis. The EMPA-KIDNEY trial showcases the efficacy of empagliflozin, a sodium-glucose cotransporter-2 (SGLT2) inhibitor, in slowing eGFR decline across diverse CKD populations, including frail individuals. Prof. Wanner advocates for the adoption of updated KDIGO guidelines recommending SGLT2 inhibitors, including empagliflozin, for CKD management, which can enhance patient outcomes and quality of life. By emphasizing early detection and comprehensive assessments, he aims to address therapeutic gaps in CKD treatment and improve healthcare practices globally.
