Multiple myeloma (MM) is an incurable hematological disease with a global incidence of 160,000 cases in 2018.^1,2 Since treatment failure among patients with relapsed/ refractory multiple myeloma (rrMM) was common with conventional therapies, additional treatment options are urgently needed to improve the survivals of these patients.^2,3 At the recently held Annual Scientific Meeting of Hong Kong Society of Myeloma, Dr. Keith Stewart revealed the merits of carfilzomib, a second-generation proteasome inhibitor, as a combination therapy to manage rrMM and highlighted the results of ARROW - the first randomized phase 3 trial comparing the efficacy and safety of twice-weekly carfilzomib + dexamethasone (Kd) regimen with the once-weekly Kd regimen.

With major advances in the management of multiple myeloma (MM), next-generation proteasome inhibitors, immunomodulatory drugs and anti-CD38 monoclonal antibodies were approved for the treatment of relapsed/refractory MM (rrMM).¹ However, Prof. Chim, Chor-Sang James noted that most patients who devel

Multiple myeloma (MM) is the second most common hematological malignancy and is associated with significant morbidity due to its end-organ destruction.¹ Despite significant treatment advances in the past couple decades, MM remains an incurable malignancy with most patients eventually experience rela

Although the median overall survival (OS) of patients with multiple myeloma (MM) has significantly improved over the past two decades, MM remains an incurable malignancy with most patients experiencing relapse and requiring additional therapy.¹ Among these patients, the presence of clonal heterogeni

In the recent DREAMM-2 study, single-agent belantamab mafodotin-blmf has demonstrated anti-myeloma activity with a manageable safety profile in patients with relapsed or refractory multiple myeloma.¹ Based on this result, the United

Multiple myeloma (MM) is a type of clonal neoplasm with substantial morbidity and mortality. With the development of better therapies, MM has transformed from untreatable to still incurable but treatable.¹

There has been a shift in the treatment paradigm for relapsed/refractory (R/R) multiple myeloma (MM) over the last decade due to the emergence of novel drugs and combination regimens. At the recent American Society of Hematology (ASH) Annual Meeting 2019,

Multiple myeloma (MM) accounts for about 10% of all hematologic malignancies.¹ In Hong Kong, the majority of MM patients are older than 65-years-old. Management of these patients needs special consideration due to age-related comorbidities.