Given its high rates of complications and mortality, hyperkalemia is traditionally difficult to manage, particularly in the emergency department (ED) setting. In a webinar on the best practice of hyperkalemia in emergency and intensive care, Professor. W. Frank Peacock discussed the prevalence and severity of hyperkalemia in the emergency medical setting, demonstrating the significance of sodium zirconium cyclosilicate (SZC) as a potassium binder to manage hyperkalemic patients safely and effectively in the ED. Rapid reduction in K⁺ (potassium ions) has not only reduced the mortality risk but also enabled emergency physicians to spend less time managing hyperkalemic patients, thus helping reduce the clinical burden of the ED.